| Ingredient | Key Function | Result |
| Capixyl™ | DHT Blocking | Biomimetic signal peptides combined with Biochanin A modulate DHT via the inhibition of 5-α reductase |
| Redensyl™ | Stem Cell Proliferation | A synergistic blend of 4 molecules that target stem cells and human fibroblasts from the dermal papilla to improve hair density |
| Procapil™ | Anti aging + hair loss prevention | Combined vitaminated matrikine with apigenin and oleanolic acid fights the follicle aging process, preventing hair loss |
| Baicapil™ | Increases hair density + reduces hair loss | Stimulates hair growth, increases hair density, reduces hair loss, and allows the recovery of a younger and healthier look |
| Acetyl Tetrapeptide-3 | Extracellular matrix stimulation | Stimulates the dermal papilla extracellular matrix proteins anchoring the hair fiber into the scalp, strengthening strands and targeting hair loss. |
| Biotinoyl Tripeptide-1 | DHT Blocking + Hair Growth | Inhibits DHT production, stimulates the production of anchoring molecules, and promotes hair growth by as much as 121%. |
| Peg-40 Hydrogenated Castor Oil | Encourages Hair Growth | Triglycerides from ricinoleic acid nurture the scalp and hair follicles encouraging healthier, faster hair growth |
Apigenin
| Anti-inflammatory + Antioxidant | Anti-inflammatory and anti-fibrotic qualities reverse the scalp fibrosis associated with baldness. |
| Oleanolic Acid | Extends Anagen Phase + Elongates Hair Shaft | Elongates the hair shaft and anagen-like stage, promoting hair growth by stimulating cell proliferation through the Wnt/β-catenin pathway |
| Glycine Soja Germ Extract | Stem Cell Activation | Enhances the metabolic activity of the cells, promoting hair growth, increasing hair density and reducing hair loss |
| Triticum Vulgare (Wheat) Germ Extract | Antioxidant + Vitamin E | Regenerates and heals strands, with high quantities of vitamin E reducing the oxidative stress linked to hair loss. |
| Scutellaria Baicalensis Root Extract | Flavonoids + Antioxidants | An effective alopecia treatment, Baicalan’s pharmaceutical properties promote hair follicle growth + oxidative stress reduction |
| Trifolium Pratense ( Red Clover) Flower Extract | DHT Blocking, Triggers Anagen Phase | Containing isoflavones, red clover mitigates issues including hair thinning and hair loss. DHT inhibiting properties stall the cycle of hair loss and trigger the growth phase. |
| Larix Europaea Wood Extract | Inhibits 5α- reductase | Specific polyphenols stimulate hair growth via the proliferation of dermal papilla cells and inhibition of 5α-reductase activity. |
| Glycine | Amino Acids + Keratin Formation | Aids tissue formation and plays an important role in keratin formation, the protein that makes up hair strands. |
| Camellia Sinensis (Green Tea) Leaf Extract | Polyphenols + Antioxidants | Phenol compounds are proven to increase the rate of hair growth. 2.5% of topical green tea extract showed substantial growth rates compared to 2.5% of Minoxidil (Lamria, 2013). |
| Arginine | Hair Growth + Regeneration | Increases scalp circulation, stimulating hair growth and regeneration. Prevents poor development of hair follicles, promoting healthier hair. |
Panthenol
| Anti-inflammatory + Hydration | Humectant-like moisturizing properties protect the hair from dehydration, adhering each strand strongly to its cuticle and penetrating deep into the cortex of the hair shaft |
| Calcium Gluconate | Hydration + Reduction of Hair Loss | Restores scalp, attracting moisture to soften, strengthen and protect hair, reducing shedding and enhancing hair growth. |
| Common Soapwort Extract H.G | Anti-Hair Loss + Anti Inflammatory | An astringent, anti-inflammatory, anti-hair loss agent that regulates sebum and soothes scalp. |
SH PLUS | ULTRA THICKENING ANTI HAIRLOSS SHAMPOO 6.8 OZ
29 Reviews
$95.00
A groundbreaking, ultra thickening shampoo, harnessing pioneering ingredients and technology to deliver our most powerful anti-hair loss treatment yet.
Our patented, lab formulated PRC PLUS compound contains 20 active ingredients, including high percentages of these four, key clinically trialed blends.
Baicapil | During studies 68.6% of volunteers experienced an increased A/T ratio, activating telogen follicles and extending the anagen phase. After three months of Baicapil application, hair loss was reduced by 60.6%. and hair density increased by 59.3%.
Capixyl | Capixyl has been shown to increase the number of hairs per centimetre by 79% after 4 months. Digital trichograms of volunteers showed + 15% growth, -52% loss and +79% density over four months.
Redensyl | After 7 and 10 days trial using Redensyl, hair growth was increased by +214% compared to untreated, and showed almost two times higher results than Minoxidil, the benchmark reference.
Procapil | During studies, 68% volunteers had an improvement in the anagen hair density, with 90% agreeing that the product favoured hair growth, and 80% experiencing a noticeable reduction in hair loss.
A further 16 dynamic, plant-based and laboratory formulated extracts work together at both cellular and dermal levels, to modulate DHT, inhibit 5-α reductase, strengthen anchoring proteins and fight the follicle aging process - stimulating growth, increasing density and allowing the recovery of a younger, thicker and healthier look.
Pioneering innovation includes a newly-discovered molecule called dihydroquercetin-glucoside (DHQG), a compound derived from plant extracts. When this biological component is combined with water, zinc and glycerin, it targets the hair follicle, encouraging the division and proliferation of the stem cells that directly lead to hair growth.
Further clinical studies and ingredients can be found in the Technology and FAQ tabs.
SH PLUS Ultra Thickening Shampoo contains 6.7 oz/200 ml.
Massage a dime size amount into wet hair and scalp. Rinse. Suitable for Daily Use
| Usage | Re-Order Frequency |
| Daily | 6 weeks |
| Five days a week | 2 months |
| Every second day | 3 months |
| Twice a week | 4 months |
Aqua (Water/Eau) Sodium Lauroyl Methyl Isethionate Butylene Glycol Lauryl Glucoside Sodium Cocoyl Isethionate Disodium Cocoamphodipropionate Fragrance/Parfum Disteareth-75 IPDI Propanediol PPG-26-Buteth-26 PEG-40 Hydrogenated Castor Oil Apigenin Oleanolic Acid Biotinoyl Tripeptide-1 Glycine Soja Germ Extract Triticum Vulgare (Wheat) Germ Extract Scutellaria Baicalensis Root Extract Acrylates/Beheneth-25 Methacrylate Copolymer Sodium Lauroyl Sarcosinate Glycol Distearate Polyquaternium-7 Amodimethicone C11-15 Pareth -7 Laureth -9 Trideceth-12 Glycerin Dextran Acetyl Tetrapeptide-3 Trifolium Pratense (Clover) Flower Extract Larix Europaea Wood Extract Zinc Chloride Glycine Camellia Sinesis Leaf Extract Sodium Metabisulfite Guar Hydroxypropyltrimonium Chloride Panthenol Gluconolactone Calcium Gluconate Phenoxyethanol Sodium Benzoate Lactic Acid Potassium Sorbate Arginine Sodium Hydroxide Citric Acid Limonene
Ships from MI, US.
| Territory | Express Shipping | $20.00 | Regular Shipping |
| U.S. | 1-3 Business Days | 3-5 Business Days (Free Shipping) |
| Canada | 2-4 Business Days | 5-7 Business Days (Paid) |
| Asia | 3-4 Business Days | 7-10 Business Days (Paid) |
| Rest-of-World | 3-5 Business Days | 7-10 Business Days (Paid) |
| Outside of metro areas: Please allow up to 2-3 additional business days for your product to arrive | ||
*Please allow 2-5 business days for order processing and dispatching.
Why is the Plus range so expensive?
Honestly, it’s a great question! Plus is potentially the most expensive Men’s anti-hair loss shampoo ever made, but it's for a very good reason. Similarly priced luxury hair care brands include costly ingredients like truffle oil, 24k gold, exotic roses, caviar and even powdered pearls, which is fancy, probably smells great, and might even be edible? But in all honesty, probably won’t do much for your hair.
The Plus range has 20 active ingredients, and the main four - Capixyl™, Redensyl™, Procapil™ and Baicapil™ are clinically proven, patented anti-hair loss formulas, rigorously tested on hair follicle stem cells and sourced from the best pharmaceutical laboratories around the world.
When we produce new products, we always strive for the latest and greatest technologies, ingredients, and formulas - but these don’t always make good business sense. Some ingredients are simply too expensive, too rare and too costly to import for us to actually use, and the price to produce them would make the RRP huge.
But this time, against our chemist and our accountants advice, we thought f*ck it. Let’s do it. We’ve made the best shampoo and conditioner on the planet, with not a single solitary shit spared for its commercial viability. Our passion is innovation, and Plus is our most impressive passion project yet.
If you didn’t want to spend $95 on a shampoo or a conditioner we wouldn’t blame you, but if you want to see where haircare will be in ten years from now, this is it. The future can quite literally be in your hands.
What is the difference between SH1 and Plus?
SH1 is still the best (reasonably priced) anti-hair loss shampoo on the market. Plus is what you get when you put SH1 on steroids!
They share the same clinically trialed ingredient, Capixyl™, and the same plant-based 5a Reductase inhibitor, Epigallocatechin Gallate extract, but SH1 has 10 additional actives, whereas Plus has 18.
SH1 is best suited to normal to thinning hair with the aim of preventing and treating mild to advanced hair loss, and Plus is best for normal to thinning hair with the aim of preventing and treating moderate to advanced hair loss.
With Plus you are getting the most anti-hair loss ingredients and growth promoting actives we could physically fit into one bottle, in the most optimal concentrations we could formulate.
How do I know which shampoo is right for me?
Do you have clinical research to back up your claims?
Sure do!
Procapil
The results of the 4-month clinical trial, covering one cycle of the telogen phase, showed a significant increase in the anagen/telogen ratio comparable to oral Finastéride® treatment in the PROCAPIL™-treated group.
Research Citations: https://ayeletgayer.com/wp-content/uploads/2021/10/Procapil_TechnEng.pdf
Containing three extremely effective plant-derived substances: oleanolic acid, which inhibits 5α1 and 5α2 reductase enzymes (extracted from olive leaves); apigenin for the vasodilation (a flavonoid that is extracted from citrus peel); and glycine-histidine-lysine peptides, which are required for pro-matrix metalloproteinase activity to be able to meet the metabolic needs of hair follicles [16].
Research Citations: https://ayeletgayer.com/wp-content/uploads/2021/10/RCP-Clinical-work.pdf
Redensyl
In a randomized, single-blinded, vehicle-controlled study of a topical active blend in the treatment of androgenetic alopecia Redensyl 7.7% had great improvement, 73.1% had moderate improvement, and 19.2% remained stable. The median self-assessment score increased from 4 at baseline to 6 at 24 weeks (P < .001), while the DLQI improved from 4 to 3, respectively (P < .001). The median anagen-to-telogen ratio increased from 2.25 to 4.00 to 6.02 at weeks 0, 12, and 24, respectively. No significant adverse events were reported. This new topical active blend is effective in the treatment of AGA, with high degree of patients' satisfaction, improvement of quality of life, and an excellent safety profile. Thus, it may represent a useful alternative therapeutic approach for AGA.
https://pubmed.ncbi.nlm.nih.gov/32473084/
Redensyl is a mix of four active ingredients: Dihydroquercetin-glucoside (DHQG), Epigallocatechin gallate glucoside (EGCG2), glycine and zinc. Glycine is essential for the hair shaft structure as it enters directly in the composition of Keratin associated protein [11].
Research Citations: https://ayeletgayer.com/wp-content/uploads/2021/10/RCP-Clinical-work.pdf
Capixyl
Capixyl is a biomimetic peptide complex that is mixed with red clover extract. It has been demonstrated to cause an increase in hair width and density [18]. Biochanin A is the major isoflavone in red clover. Biochanin A is known to be an effective inhibitor of 5αreductase type I & II activity [36].
Research Citations: https://ayeletgayer.com/wp-content/uploads/2021/10/RCP-Clinical-work.pdf
Baicalan
Baicalin is a traditional Chinese herbal medicine commonly used for hair loss, the precise molecular mechanism of which is unknown. In the present study, the mechanism of baicalin was investigated via the topical application of baicalin to reconstituted hair follicles on mice dorsa and evaluating the effect on canonical Wnt/β-catenin signaling in the hair follicles and the activity of dermal papilla cells.
Research Citations: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810219/
Biotinyl-GHK
Biotinyl-GHK (vitamin-carrying peptide) is formed from biotin (vitamin H). The deficiency of this vitamin leads to thin hair, alopecia, loose skin, and dermatitis [17].
Research Citations: https://ayeletgayer.com/wp-content/uploads/2021/10/RCP-Clinical-work.pdf
Amino Acids
Amino Acids HK‐Cu increases cell adhesion and integrity of the dermal‐epidermal junction, 23 providing mechanical tension on the fibroblasts, which is known to enhance production of collagen, ECM proteins and proteoglycans. 24 The mechanism of GHK‐Cu is unclear, because at times it appears to be merely a vehicle for copper transport, whereas it can also be argued that it is a signaling molecule in its own right. 25
Despite being a promoter of wound healing and collagen synthesis, GHK‐Cu suppresses the expression of TGF‐β1, 26 which is overexpressed in balding scalps. This is probably the mechanism of hair shaft thickening and hair growth support observed from subcutaneously delivered GHK‐Cu. A similar tripeptide, AHK‐Cu, also yielded the same outcome in vitro, that includes reduced expression of TGF‐β1 and increased hair shaft elongation, increased expression of vascular endothelial growth factor and reduced negative growth factors. 27
Research Citations: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8332470/
Biochanin A, Acetyl tetrapeptide-3
The non-significant difference in clinical efficacy and safety to 3% minoxidil solution suggests that the herbal extract combination evaluated here could potentially be an alternative treatment for AGA.
Research Citations: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840088/
Biochanin A
Blocks the conversion of testosterone to DHT preventing the shortening of the hair cycle and hair follicle miniaturization.
Research Citations:
https://www.ncbi.nlm.nih.gov/pubmed/23449130
Acetyl Tetrapeptide-3
Improves ECM protein integrity in dermal papilla for better hair anchoring. The efficacy studies seem to indicate the hair follicles are longer and thicker with treatment. It reduces damages caused by inflammation. It shows an increase in the anagen stage of hair growth, and a decrease in the telogen phase.
Research Citations: http://www.redenhair.com/img/cms/CAPIXYL-Techfile.pdf
